SEARCH TERM: VEGF
Gene Overview
The VEGF gene family plays a vital role in the development, maintenance, and repair of blood vessels. These genes are involved in processes such as angiogenesis (growth of new blood vessels), vascular permeability, and cell survival. VEGF activity is crucial in various tissues and organs, affecting cardiovascular health, immune response, and recovery from injury. Variants in these genes can impact blood vessel growth, inflammatory pathways, and tissue repair.
VEGF -634 G>C
Impact Allele: C allele
Impact
C allele (negative)
- Vascular Health:
- Associated with increased VEGF levels, leading to higher blood vessel permeability and vasodilation.
- Linked to poor coronary artery disease (CAD) outcomes, potentially due to the promotion of blood clotting pathways, smooth muscle growth, and inflammation factors.
- Exercise Physiology:
- Higher levels of baseline VO2 max were observed in C allele carriers.
Next Steps:
- Consult your genomics specialist or doctor to evaluate cardiovascular health risks.
- Focus on anti-inflammatory diets and lifestyle interventions to mitigate potential risks.
- Regular exercise may help optimize VO2 max benefits.